Categoría de Archivos: Malvern Panalytical

Drug product developers face many challenges as they seek to develop new drug products based on novel dosage forms or delivery technologies. This particularly true of Orally Inhaled and Nasal Drug Products (OINDPs), where developers must not only develop an effective formulation but also understand how this can be reproducibly delivered to a patient using … Leer Más Accelerating the Development of Orally Inhaled and Nasal Drug Products (OINDPs) →

The last webinar in this series will elaborate on the value of Nanoparticle Tracking Analysis (NTA) to the development of vaccines, including the characterization of VLPs (several Virus Like Particles being developed as vaccines to COVID19).  More than a simple particle size analysis, the ability to rapidly make total (not just infective) particle concentration measurements … Leer Más Focus on Vaccine Development 4 – Virus: Vaccine and VLP Characterization with Nano-particle Tracking Analysis (NTA) →

Join us from the comfort of your own home! This webinar will provide an overview of the NanoSight NS300 for nanoparticle size and concentration measurements using Nanoparticle Tracking Analysis (NTA). You will get to see the instrument and software performing tests, demonstrating the easy-to-use yet advanced capabilities of NanoSight. Summary Date:May 19 2020 – May … Leer Más Demo at your Desk: Nano-particle Size & Concentration Measurements →

Ever-more structurally complex bio-molecules and biological entities coming in focus of pharma development warrant growing requirements for fit-for-purpose analytics and extended characterization through orthogonal use of multiple technologies. Viruses have long been used in vaccine development as delivery vehicles or attenuated and inactivated vaccines. They are also increasingly used as vectors in gene therapy. Recombinant … Leer Más Delving Deeper Into AAV Attributes: Enhanced Characterization Using Multiple Technologies →

We have developed a fast, convenient and precise methodology using isothermal titration calorimetry (ITC) to elucidate the enzymatic properties of the soluble epoxide hydrolase (sEH) and characterise its inhibition. sEH catalyses epoxy lipid hydrolysis and is implicated in cardiovascular diseases, diabetes and pain. The ITC-based single injection methodology (SIM) is based on measuring the heat … Leer Más Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide →